Donepezil: Information on the Drug

What is Donepezil? Donepezil is a prescription medication that treats confusion associated with Alzheimer’s disease. This medication is not a treatment for Alzheimer’s disease, but it improves mental function and awareness. It blocks the enzyme, and by doing this, Donepezil restores the balance of natural substances in the brain. Donepezil is not an option thatRead More


What is Donepezil?

Donepezil is a prescription medication used to treat confusion associated with Alzheimer’s disease. It improves mental function and awareness by blocking certain enzymes in the brain and restoring the balance of natural substances.

Donepezil may have different effects on different individuals. While some experience improved mental function, others may see no change or even a worsening of symptoms. It is important to note that Donepezil is not a cure for Alzheimer’s disease and may have other uses not listed here.

Important Information

It is crucial to carefully read and follow the instructions for using this medication. Consult with your doctor if you have any allergies or concerns before taking Donepezil.

Inform your doctor about all current medications you are taking, as some may interact with Donepezil and cause severe side effects.

Your doctor will determine if Donepezil therapy is suitable for you.

Ensure you attend all necessary appointments with your doctor during the treatment. Do not share your medication with others, as it can be dangerous. If you have any doubts about dosing or any other aspect of the medication, consult with your doctor.

Your doctor may adjust your dosage or discontinue the medication if it is not suitable for you.

What to Know Before Taking Donepezil?

If you are allergic to Donepezil or any other drugs, consult with your doctor before taking this medication.

Inform your doctor if you have or have had:

  • Asthma or other breathing disorders
  • A heart rhythm disorder
  • A stomach ulcer
  • Urination problems
  • Trouble swallowing tablets
  • Liver or kidney disease
  • A seizure

If you are pregnant or breastfeeding, consult with your doctor before taking this medication.

Inform your doctor if you weigh less than 55kg (120 lb) or have a history of bleeding in the intestine or stomach, seizures, irregular heartbeat, difficulty urinating, asthma, kidney, liver, or heart disease.

How to Take Donepezil?

Clear any doubts you have about this medication by reading the instruction manual provided. Follow your doctor’s directions carefully.

You can take Donepezil with or without food, as advised by your doctor based on your medical condition.

Swallow the whole tablet without chewing, crushing, or breaking it. If you have difficulty swallowing the tablet, consult with your doctor.

Donepezil does not cure Alzheimer’s disease but helps control its symptoms. Do not stop taking Donepezil without consulting your doctor. If you feel well, consult with your doctor before discontinuing Donepezil therapy.

Your doctor will determine the appropriate dosage for you. They may start with a lower dosage and adjust it over time. Follow your doctor’s instructions for Donepezil therapy.

If you require dental work or surgery, inform your dentist or surgeon about your current medication, including Donepezil. Your surgeon may advise temporarily stopping Donepezil.

Donepezil Dosage

Usual Adult Dosage of Donepezil for Alzheimer’s Disease:

The initial dosage of Donepezil is 5mg orally once daily at bedtime.

For mild to moderate Alzheimer’s disease, the starting dosage is 10mg orally once daily. After a period of time, the dosage may be reduced to 5mg once daily for 4 to 6 weeks.

For moderate to severe Alzheimer’s disease, the maintenance dosage is 23mg once daily. After the maintenance dosage, the initial dosage is 10mg once daily for three months.


If you accidentally take an excessive amount of Donepezil, seek immediate medical attention. Contact your doctor for guidance on managing the overdose.

Symptoms of Donepezil overdose include vomiting, severe nausea, blurred vision, sweating, shallow breathing, slow heartbeat, muscle weakness, seizures, or fainting. If you experience any of these symptoms, seek medical help immediately.

What to Avoid While Using Donepezil?

You can continue your regular diet unless instructed otherwise by your doctor.

Avoid operating heavy machinery or driving if you feel drowsy or dizzy due to the medication. Donepezil may cause drowsiness and increase the risk of accidents.

Avoid consuming alcohol while taking Donepezil, as it can intensify drowsiness and potentially harm


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