Raloxifene: Information about the Drug

Raloxifene: Information about the Drug

What is Raloxifene?

Raloxifene, also known by its brand name Evista, is a medication classified as a Selective Estrogen Receptor Modulator (SERM). It is prescribed by doctors to treat osteoporosis in postmenopausal women. Raloxifene can also be used to reduce the risk of breast cancer and other conditions as determined by a doctor. This medication is available in oral form and requires a prescription.

Important Information

Raloxifene is just one part of a comprehensive treatment program that may include dietary changes, regular exercise, bone mineral density testing, and calcium and vitamin D supplements. It is important to closely follow your doctor’s instructions.

What to know before taking Raloxifene?

Avoid taking Raloxifene if you are allergic to it or any of its components, or if you have a history of blood clots, high triglycerides caused by estrogen use, liver disease, kidney disease, endometriosis, abnormal vaginal bleeding, or have not gone through menopause. Inform your doctor about any heart problems, irregular heartbeats, heart attack or stroke history, high blood pressure, cancer, or smoking habits. Pregnant women and breastfeeding mothers should not use Raloxifene as it may harm the baby.

How to take Raloxifene?

Take Raloxifene exactly as prescribed by your doctor. Follow all instructions on the prescription label and medication guide carefully. Do not exceed the recommended dosage and maintain consistency throughout the treatment. If there is no improvement in your condition, consult your doctor. Inform your doctor in advance if you require urgent surgery, as they may advise you to temporarily stop taking Raloxifene. Regular check-ups and self-examination of the breasts are recommended during treatment. Store the medication at room temperature, away from heat and moisture, and keep it out of children’s reach. Dispose of any leftover medication properly after completing the treatment.

Raloxifene dosage

The dosage of Raloxifene prescribed by your doctor depends on various factors such as age, weight, symptoms, the severity of the condition, other medical issues, and concurrent medications. The doctor may adjust the dosage based on individual patient needs.


If you experience any discomfort while taking Raloxifene, consult your doctor or seek medical assistance. In case of overdose, there are no specific symptoms, but you can contact the poison helpline at 1-800-222-1222.

What to avoid while using Raloxifene?

Avoid long journeys while on this medication and do not exceed the recommended calcium supplement dosage to prevent kidney stones.

Raloxifene side effects

Common side effects of Raloxifene include hot flashes, leg cramps, swelling in hands, ankles, and feet, joint pain, flu-like symptoms, and increased sweating. If these symptoms become bothersome or unbearable, consult your doctor for medical assistance. Stop taking the medication and inform your doctor if you experience breast swelling or tenderness, stroke symptoms (such as weakness or numbness, slurred speech, vision problems), signs of blood clot in the lungs (chest pain, difficulty breathing, coughing up blood), signs of blood clot in the body (swelling, warmth, redness in arms or legs), urinary problems, or loss of coordination. Report any new symptoms or worsening of existing symptoms to your doctor.

What drugs can interact with Raloxifene?

Inform your doctor about all over-the-counter medications, including vitamins, nutritional supplements, herbal products, and other medications you have taken recently or are currently taking. Some medications that may interact with Raloxifene include cholestyramine, warfarin, birth control pills, hormone replacement therapy, and other over-the-counter medicines.

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