Accupril: Details about the Medication

Accupril: Details about the Medication

What is Accupril?

Accupril is a brand-name medication that contains the drug quinapril, which is an ACE inhibitor. It is used to treat high blood pressure by widening and relaxing blood vessels. By reducing blood pressure, it can lower the risk of heart attack or stroke. It is also commonly prescribed for heart failure.

Important Information

Accupril should not be used during pregnancy, and if you become pregnant while taking the medication, you should stop immediately and inform your doctor. Individuals with angioedema or those taking sacubitril-containing medications should also avoid using Accupril. Additionally, caution should be exercised when combining Accupril with aliskiren-containing medications in individuals with diabetes.

What to know before taking Accupril?

Do not take Accupril if you are allergic to it, have a history of angioedema, or have recently taken sacubitril. Consult with your doctor about the safety of this medication if you have a connective tissue disease, liver disease, kidney disease, congestive heart failure, or heart disease. Accupril is not suitable for individuals under 18 years old and may not be safe to use while breastfeeding.

How to take Accupril?

Take Accupril exactly as prescribed by your doctor. Follow the directions on the prescription label and do not take more or less of the medication than recommended. Your doctor may adjust the dosage to ensure optimal benefits. Regular blood pressure checks and kidney/liver function tests may be necessary during treatment. Inform your doctor if you experience ongoing diarrhea, vomiting, or excessive sweating as these can lead to dehydration and other complications. If you are scheduled for surgery, inform your surgeon about your use of Accupril. It may be necessary to temporarily stop the medication. Individuals with high blood pressure may need to take Accupril indefinitely, as high blood pressure often has no symptoms.

Accupril dosage

The dosage of Accupril varies depending on factors such as age, condition being treated, severity of the problem, and individual response. For high blood pressure without diuretic use, the starting dose is typically between 10mg and 20mg, which may be increased up to 80mg per day. For high blood pressure with diuretic use, the starting dose is 5mg. The initial dose for heart failure is 5mg, which may be gradually increased to 20-40mg per day.


In case of an Accupril overdose, seek emergency medical assistance by calling 911 or contacting the Poison helpline at 1-800-222-1222. Symptoms of overdose may include nausea, tingling sensation, tiredness, and muscle weakness.

What to avoid while using Accupril?

Avoid drinking alcohol while taking Accupril as it can further lower blood pressure and increase the medication’s side effects. Do not take salt substitutes or potassium supplements without consulting your doctor. When transitioning from a sitting to a standing position, do so slowly to prevent dizziness and potential falls.

Accupril side effects

Accupril can cause mild to severe side effects, although not everyone experiences them. Common side effects may include back pain, skin rash, muscle pain, headache, diarrhea, difficulty breathing, low blood pressure, chest pain, stomach pain, nausea, vomiting, coughing, fatigue, and dizziness. Serious side effects may include angioedema (characterized by stomach pain, trouble swallowing, trouble breathing, and swelling of the throat, tongue, lips, or face), liver failure (indicated by nausea, vomiting, abdominal pain, and yellowing of the eyes and skin), and increased potassium levels (resulting in tingling sensation, tiredness, and muscle weakness). If you experience any severe symptoms, stop taking Accupril and seek immediate medical attention.

What drugs can interact with Accupril?

Accupril can interact with various medications, including high blood pressure medications, diuretics, potassium supplements, mood stabilizing medicines like lithium, arthritis and pain medications, and others. It is important to inform your doctor about all the medications you are taking to avoid any potential interactions or adverse effects.

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